Emeruwa A C
J Nat Prod. 1982 Mar-Apr;45(2):123-7. doi: 10.1021/np50020a002.
Ripe and unripe Carica papaya fruits (epicarp, endocarp, seeds and leaves) were extracted separately and purified. All the extracts except that of leaves produced very significant antibacterial activity on Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa and Shigella flexneri. The MIC of the substance was small (0.2-0.3 mg/ml) for gram-positive bacteria and large (1.5-4 mg/ml) for gram-negative bacteria. The substance was bactericidal and showed properties of a protein. Other proteins previously found in C. papaya did not show antibacterial activity.
成熟和未成熟的番木瓜果实（外果皮、内果皮、种子和叶子）分别进行提取和纯化。除叶子提取物外，所有提取物对金黄色葡萄球菌、蜡样芽孢杆菌、大肠杆菌、铜绿假单胞菌和弗氏志贺菌均表现出非常显著的抗菌活性。该物质对革兰氏阳性菌的最低抑菌浓度较小（0.2 - 0.3毫克/毫升），对革兰氏阴性菌的最低抑菌浓度较大（1.5 - 4毫克/毫升）。该物质具有杀菌作用，并表现出蛋白质的特性。先前在番木瓜中发现的其他蛋白质未表现出抗菌活性。
