Stille W T, Tabershaw I R
J Occup Med. 1982 Jun;24(6):480-4.
Deaths for a 31-year period (1948-1978) were analyzed in a historical prospective cohort study of 655 white male talc workers. Death rates from all causes, from cancer of the respiratory system, and from nonmalignant respiratory disease were not significantly different from those of the U.S. white male population. However, significant differences for these causes of death were found among workers who had previous occupational histories. An analysis of the latency periods of the observed lung cancer suggests that exposure to an etiologic agent during previous work experience may play a role in the development of lung cancer.
在一项对655名白人男性滑石粉工人的历史性前瞻性队列研究中,分析了31年期间(1948年至1978年)的死亡情况。所有原因、呼吸系统癌症和非恶性呼吸系统疾病的死亡率与美国白人男性人群的死亡率无显著差异。然而,在有既往职业史的工人中,发现这些死因存在显著差异。对观察到的肺癌潜伏期的分析表明,既往工作经历中接触致病因子可能在肺癌的发生中起作用。