Chadee K C, Dick T A
J Parasitol. 1982 Jun;68(3):451-6.
Biological characteristics of Trichinella isolate (wolverine: 55 degrees 00'N, 100 degrees 00'W, 1979) were established in Crl: COBS CFW (SW) mice. Comparison of the wolverine isolate's biological characteristics with another Trichinella isolate (polar bear), both from closely related geographic areas, revealed there were stable and reproducible genetic differences between isolates. Differences were most pronounced for degree of infections causing a 50% mortality of mice, larval production by females in vitro, reproductive capacity indices, and survival of muscle larvae. Species and strain of host altered characteristics of the wolverine isolate such as worm position, sex ratios, % recovery, larval production by females in vitro, and reproductive capacity indices. Genetic differences between isolates of Trichinella and interaction with host genetics raises interesting questions on Trichinella speciation. Differences reported here, are best interpreted for the time being at least, as part of the normal biological variability of the species Trichinella spiralis.
旋毛虫分离株（狼獾：北纬55°00′，西经100°00′，1979年）的生物学特性在Crl:COBS CFW(SW)小鼠中得以确定。将该狼獾分离株的生物学特性与另一个来自密切相关地理区域的旋毛虫分离株（北极熊）进行比较，结果显示分离株之间存在稳定且可重复的遗传差异。这些差异在导致小鼠50%死亡率的感染程度、雌性体外产幼虫情况、繁殖能力指数以及肌幼虫存活率方面最为明显。宿主的种类和品系改变了狼獾分离株的特性，如虫体位置、性别比例、回收率、雌性体外产幼虫情况以及繁殖能力指数。旋毛虫分离株之间的遗传差异以及与宿主遗传学的相互作用，引发了关于旋毛虫物种形成的有趣问题。此处报道的差异，至少目前最好解释为旋毛形线虫物种正常生物学变异性的一部分。
