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法医毒理学的进展:超越分析化学

Progress in forensic toxicology: beyond analytical chemistry.

作者信息

Finkle B S

出版信息

J Anal Toxicol. 1982 Mar-Apr;6(2):57-61. doi: 10.1093/jat/6.2.57.

DOI:10.1093/jat/6.2.57
PMID:7098448
Abstract

The dominant role of analytical chemistry in applied forensic toxicology is described briefly from an historical perspective. It is argued, however, that obligations imposed on forensic toxicologists by the law, medicine, and society for understanding toxicity in an increasing variety of case problems is really the major challenge and obligation facing toxicologists today. Case examples and rationale are presented in support of this argument. Needs and possible solutions to redress the current professional imbalance are suggested; such as a program to monitor prospectively adverse drug actions and interactions, forensic toxicology reference centers, graduate training programs, and collaborative research involving analytical toxicologists and biomedical researchers, including pathologists. There is a need to develop an industrial, governmental, and professional partnership. These proposals are discussed and justified.

摘要

从历史角度简要描述了分析化学在应用法医毒理学中的主导作用。然而,有人认为,法律、医学和社会对法医毒理学家在越来越多的案例问题中理解毒性所施加的义务,才是当今毒理学家面临的主要挑战和义务。文中给出了案例示例和理由来支持这一论点。还提出了纠正当前专业失衡的需求和可能的解决方案;比如前瞻性监测药物不良反应和相互作用的项目、法医毒理学参考中心、研究生培训项目,以及包括分析毒理学家和生物医学研究人员(包括病理学家)在内的合作研究。有必要建立产业、政府和专业领域的伙伴关系。对这些提议进行了讨论并说明了其合理性。

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