Gartel' A L, Ghaplygina N M, Ponomareva T I, Tiunnikov G I, Dreĭzin R S
Mol Biol (Mosk). 1982 May-Jun;16(3):519-27.
Four cell lines transformed by simian adenovirus SA7 and its DNA were analysed by means of molecular hybridization. Content of viral DNA sequences in different lines varied from 10% (the left end) of the molecule to the entire genomes. Transcription of the D BglII fragment (coordinates 1.8--10) was observed in all examined lines. The integration type of highly oncogenic simian adenovirus SA7 DNA differed from the pattern of integration of the highly oncogenic human adenovirus type 12 and was similar to that of the non-oncogenic adenoviruses in adenovirus-transformed cells.
利用分子杂交技术分析了由猿猴腺病毒SA7及其DNA转化的4种细胞系。不同细胞系中病毒DNA序列的含量从分子的10%（左端）到整个基因组不等。在所有检测的细胞系中均观察到D BglII片段（坐标1.8 - 10）的转录。高度致癌的猿猴腺病毒SA7 DNA的整合类型不同于高度致癌的人腺病毒12型的整合模式，并且与腺病毒转化细胞中无致癌性的腺病毒的整合模式相似。
