Petrenko V A, Spirin G V
Mol Biol (Mosk). 1982 May-Jun;16(3):644-8.
The reaction of cytidylic acid with O-delta-aminooxybuthylhydroxylamine H2NO(CH2)4ONH2 (delta-HA) was studied. The reaction occurs in agreement with the mechanism of the cytidine and hydroxylamine or O-methylhydroxylamine interaction and results in appearance of two compounds: 4-O-delta-aminooxybuthyloxyme of 6-O-delta-aminooxybuthoxyamino-5,6-dihydrouridine-5'-phosphate and 4-O-delta-aminooxybuthyloxyme of uridine-5'-phosphate. These products are produced in pure form by gel-chromatography and these structures are evidenced by UV- and PMR-spectroscopy and by reaction with acetone. The kinetics of correspondent reaction was studied by UV-spectroscopy.
研究了胞苷酸与O-δ-氨基氧基丁基羟胺H2NO(CH2)4ONH2（δ-HA）的反应。该反应按照胞苷与羟胺或O-甲基羟胺相互作用的机理进行，生成两种化合物：6-O-δ-氨基氧基丁氧基氨基-5,6-二氢尿苷-5'-磷酸的4-O-δ-氨基氧基丁基醚和尿苷-5'-磷酸的4-O-δ-氨基氧基丁基醚。这些产物通过凝胶色谱法以纯形式制备，其结构通过紫外光谱和核磁共振光谱以及与丙酮的反应得到证实。通过紫外光谱研究了相应反应的动力学。
