Ulanov B P, Matorina T I, Gonikberg E M
Mol Biol (Mosk). 1980 Mar-Apr;14(2):390-401.
The interaction of a O-derivated analog of hydroxylamine-O-beta-diethylaminoethyl-hydroxylamine (OHA) with bacteriophage SD DNA in situ was studied. It was established that OHA modifies the cytidine of phage DNA up to 2% from the total cytidine quantity. The terminal ratio products of modification cytidine corresponds to the ration of modification products for completely denaturated DNA. The results obtained are interpreted in terms of locally denaturated regions spaced in the whole genome of SD bacteriophage.
研究了羟胺 - O - β - 二乙氨基乙基羟胺（OHA）的O - 衍生物类似物与噬菌体SD DNA在原位的相互作用。已确定OHA可使噬菌体DNA的胞嘧啶修饰量达到总胞嘧啶量的2%。修饰胞嘧啶的末端比率产物与完全变性DNA的修饰产物比率相对应。所获得的结果是根据SD噬菌体全基因组中分布的局部变性区域来解释的。
