猫快速眼动（REM）睡眠期间的杏仁核点燃。

Amygdaloid kindling during rapid eye movement (REM) sleep in cats.

作者信息

Calvo J M, Alvarado R, Briones R, Paz C, Fernandez-Guardiola A

出版信息

Neurosci Lett. 1982 Apr 26;29(3):255-9. doi: 10.1016/0304-3940(82)90326-3.

Abstract

Development of amygdaloid kindling was analyzed during REM sleep and during wakefulness. Daily evolution of electrographic and behavioral changes was significantly delayed in REM kindled rats. The number of kindling trials required to reach the first generalized convulsive seizure was also significantly increased in comparison with awake kindled animals. Changes in sleep organization were measured under REM kindling conditions. A significant increase in total sleep time and in the percentage of light slow-wave sleep was found during the kindling process. No significant sleep changes were observed in REM-established kindling. REM inhibitory influence over epileptogenesis is discussed.

摘要

在快速眼动睡眠（REM）和清醒状态下分析杏仁核点燃的发展情况。在REM点燃的大鼠中，脑电图和行为变化的每日演变明显延迟。与清醒状态下点燃的动物相比，达到首次全身性惊厥发作所需的点燃试验次数也显著增加。在REM点燃条件下测量睡眠结构的变化。在点燃过程中发现总睡眠时间和轻度慢波睡眠百分比显著增加。在REM建立的点燃中未观察到明显的睡眠变化。讨论了REM对癫痫发生的抑制作用。