Krohel G B, Krauss H R, Winnick J
Ophthalmology. 1982 May;89(5):492-8. doi: 10.1016/s0161-6420(82)34763-6.
Fifteen cases of orbital abscess were reviewed. Significant morbidity occurred despite treatment with intravenous antibiotics and surgical drainage. The complications included visual loss to less than 20/200 (four patients), residual proptosis (two patients), residual diplopia (two patients), osteomyelitis (one patient), and death (one patient). Seven patients reported no pain. Fever was absent in eight patients. Four patients had normal white blood cell counts. Many of these patients had received inappropriate or inadequate doses of oral antibiotics before referral. Partially treated cases of orbital abscess may not manifest the expected clinical findings of orbital infection. Four patients presented in an insidious fashion with symptoms evolving over weeks to months. Their subacute presentations in the absence of fever, pain, or elevated white blood cell count mimicked the onset of orbital tumors. CT scan failed to detect an abscess in two cases. Conjunctival and nasal cultures were not helpful in determining the bacteriologic etiology of these infections. Surgical drainage and appropriate antibiotic therapy is the definitive treatment of orbital abscess.
回顾了15例眼眶脓肿病例。尽管采用了静脉抗生素治疗和手术引流,但仍出现了严重的发病情况。并发症包括视力降至20/200以下(4例患者)、残留眼球突出(2例患者)、残留复视(2例患者)、骨髓炎(1例患者)和死亡(1例患者)。7例患者报告无疼痛。8例患者无发热。4例患者白细胞计数正常。这些患者中有许多在转诊前接受了不适当或剂量不足的口服抗生素治疗。部分治疗的眼眶脓肿病例可能未表现出眼眶感染预期的临床症状。4例患者以隐匿方式就诊,症状在数周至数月内逐渐发展。他们在无发热、疼痛或白细胞计数升高的情况下出现亚急性表现,类似于眼眶肿瘤的发病。CT扫描在2例病例中未能检测到脓肿。结膜和鼻腔培养对于确定这些感染的细菌学病因并无帮助。手术引流和适当的抗生素治疗是眼眶脓肿的决定性治疗方法。