Winter J, Donald D, Bennett B, Douglas A S
Postgrad Med J. 1982 Feb;58(676):108-9. doi: 10.1136/pgmj.58.676.108.
The case is described of a young man with probable familial antithrombin III deficiency, a disorder associated with a marked predisposition to venous thrombo-embolic events. In addition to a history of venous thrombosis and pulmonary embolism, at post-mortem this patient demonstrated widespread arterial thrombosis and atheroma. The probable association of severe arterial thrombosis and atheroma with a clearly definable coagulation disorder predisposing to thrombosis is of interest.
本文描述了一名患有可能的家族性抗凝血酶III缺乏症的年轻男子，该病症与静脉血栓栓塞事件的显著易感性相关。除了有静脉血栓形成和肺栓塞病史外，该患者在尸检时还表现出广泛的动脉血栓形成和动脉粥样硬化。严重动脉血栓形成和动脉粥样硬化与一种明确可定义的易导致血栓形成的凝血障碍之间可能存在的关联令人关注。
