Scott D L, Roden S, Low-Beer T S, Takavarasha L
Postgrad Med J. 1982 Mar;58(677):146-8. doi: 10.1136/pgmj.58.677.146.
Thirty-six patients with rheumatoid arthritis were allocated at random to one of 3 groups prescribed 4 different non-steroidal anti-inflammatory drugs (NSAID). Each drug was given for one week over 4 consecutive weeks in a balanced order. The patients were then asked to select one NSAID for continuation therapy and were followed-up 6 months later. The success of the patient selection method was compared with that of physician selection by retrospectively surveying NSAID prescribing in 164 patients attending 2 other rheumatology units over a 5-year period. Only 72% of patients in the prospective study felt able to choose one of the NSAIDs and 31% of these had discontinued the chosen drug within 6 months. In the retrospective study, 40% changed their NSAID within 6 months.
36例类风湿性关节炎患者被随机分配到3组中，每组使用4种不同的非甾体抗炎药（NSAID）中的一种。每种药物按平衡顺序连续4周，每周服用1周。然后让患者选择一种NSAID进行持续治疗，并在6个月后进行随访。通过回顾性调查另外2个风湿病科5年内164例患者的NSAID处方情况，将患者选择方法的成功率与医生选择方法的成功率进行比较。在前瞻性研究中，只有72%的患者觉得能够选择一种NSAID，其中31%的患者在6个月内停用了所选药物。在回顾性研究中，40%的患者在6个月内更换了NSAID。
