Dornberger K, Lich H
Pharmazie. 1982 Mar;37(3):215-21.
693 kinds of indigenous plants randomly selected were screened for their antimicrobial activities against 23 different test organisms (Gram-positive, Gram-negative bacteria, yeast and fungi). The results of the testing showed that 250 (36%) kinds of the plants belonging to 72 families exhibited some level of antimicrobial action in vitro. Moreover, a microbiological prescreening program was employed in search of presumed cancerostatic plant products in crude extracts. These microbial tests based on agar diffusion techniques consist of prophage induction test and BIP test (bacteria inhibition-induction-phage inhibition). All active components selected by these microbial models are potential inhibitors of nucleic acid metabolism. A wide variety of plants was demonstrated to exhibit interesting activities in these screening systems. The bioactivity is uniformly distributed in various order. The screening results are briefly discussed.
对随机选取的693种本土植物进行了针对23种不同测试微生物（革兰氏阳性菌、革兰氏阴性菌、酵母和真菌）的抗菌活性筛选。测试结果表明，属于72个科的250种（36%）植物在体外表现出一定程度的抗菌作用。此外，还采用了微生物预筛选程序来寻找粗提物中可能的抗癌植物产品。这些基于琼脂扩散技术的微生物测试包括原噬菌体诱导试验和BIP试验（细菌抑制-诱导-噬菌体抑制）。通过这些微生物模型筛选出的所有活性成分都是核酸代谢的潜在抑制剂。在这些筛选系统中，多种植物被证明具有有趣的活性。生物活性在不同类别中均匀分布。对筛选结果进行了简要讨论。
