Jaeger R J, Cote I L
Res Commun Chem Pathol Pharmacol. 1982 May;36(2):345-8.
The modifying effects of hypoxia (7% 02) on acute lethality; and concentration of tissues non-protein sulfhydryls (NPSH) after acrylonitrile (ACN) exposure were studied. Hypoxia plus ACN exposure in male rats produced a substantial increase in mortality and a greater decrease in NPSH than ACN or hypoxia alone. NPSH in blood did not decrease significantly as a result of hypoxia, ACN or the combination.
研究了低氧（7%氧气）对丙烯腈（ACN）暴露后急性致死率及组织非蛋白巯基（NPSH）浓度的修饰作用。雄性大鼠低氧加ACN暴露导致死亡率大幅增加，且与单独ACN暴露或低氧相比，NPSH的降低幅度更大。低氧、ACN或二者联合作用后，血液中的NPSH没有显著降低。
