Werder M, Ruppert R K, Bajc O, Truniger B
Schweiz Med Wochenschr. 1982 May 22;112(21):765-9.
Central pontine myelinolysis (CPM) occurred in a typical patient with severe alcoholism presenting with severe initial hyponatremia and a rapidly progressive pontomesencephalic syndrome. A review on 141 cases of CPM is presented and the ties between CPM, hyponatremia/hypoosmolality and the syndrome of inadequate secretion of ADH are discussed. Correct interpretation of the patient's history (alcoholism, severe wasting disease) and the clinical picture (initial hypoosmolality with acute or subacute pontomesencephalic syndrome, possibly locked-in syndrome) should permit correct in-vivo diagnosis more frequently than hitherto.
中央桥脑髓鞘溶解症（CPM）发生在一名典型的严重酒精中毒患者身上，该患者最初表现为严重低钠血症，并伴有快速进展的桥脑-中脑综合征。本文对141例CPM病例进行了综述，并讨论了CPM、低钠血症/低渗血症与抗利尿激素分泌不足综合征之间的关系。正确解读患者病史（酒精中毒、严重消耗性疾病）和临床表现（最初的低渗血症伴急性或亚急性桥脑-中脑综合征，可能为闭锁综合征），应比以往更频繁地实现正确的活体诊断。
