• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Isolation and partial characterization of a toxin from the venom of the East African orthognath spider Pterinochilus spec.

作者信息

Bachmann M

出版信息

Toxicon. 1982;20(3):547-52. doi: 10.1016/0041-0101(82)90048-4.

DOI:10.1016/0041-0101(82)90048-4
PMID:7101305
Abstract

A minor basic polypeptide in the venom of the East African orthognath spider Pterinochilus spec. was the most toxic of 16 basic components in this venom. This toxin A4/4 was purified by gel permeation on Sephadex G-50 and ion exchange chromatography on CM-Sephadex C-25 with a yield of 1.3% of the total protein content of the crude venom. The polypeptide has an isoelectric point of 9.39 and molecular weight of 10,500. The s.c. LD50 in mice is 0.1 mg/kg. Death occurred due to respiratory paralysis. After administration of sublethal doses rapid reversibility of the symptoms and total recovery of the animals was observed.

摘要

相似文献

1
Isolation and partial characterization of a toxin from the venom of the East African orthognath spider Pterinochilus spec.
Toxicon. 1982;20(3):547-52. doi: 10.1016/0041-0101(82)90048-4.
2
Adenosine triphosphate in tarantula spider venoms and its synergistic effect with the venom toxin.狼蛛毒液中的三磷酸腺苷及其与毒液毒素的协同作用。
Toxicon. 1975 Feb;13(1):61-6. doi: 10.1016/0041-0101(75)90159-2.
3
Isolation of a pure toxic polypeptide from the venom of the spider Phoneutria nigriventer and its neurophysiological activity on an insect femur preparation.从巴西游走蛛毒液中分离出一种纯毒性多肽及其对昆虫股骨标本的神经生理活性。
Toxicon. 1982;20(6):1059-67. doi: 10.1016/0041-0101(82)90108-8.
4
Tarantula (Eurypelma californicum) venom, a multicomponent system.狼蛛（加州捕鸟蛛）毒液，一种多组分体系。
Biol Chem Hoppe Seyler. 1989 May;370(5):485-98. doi: 10.1515/bchm3.1989.370.1.485.
5
Isolation of neurotoxic peptides from the venom of the 'armed' spider Phoneutria nigriventer.从“武装”蜘蛛黑腹捕鸟蛛毒液中分离神经毒性肽。
Toxicon. 1991;29(10):1225-33. doi: 10.1016/0041-0101(91)90195-w.
6
[Toxic components of the venom of the cellar spider Segestria florentina].
Bioorg Khim. 1987 Aug;13(8):1013-8.
7
Partial characterization of lethal and neuroactive components of the brown recluse spider (Loxosceles reclusa) venom.
Toxicon. 1979;17(4):347-54. doi: 10.1016/0041-0101(79)90262-9.
8
Purification and chemical characterization of the major neurotoxin from the venom of Pelamis plautrus.来自扁尾海蛇毒液的主要神经毒素的纯化及化学特性分析。
Biochemistry. 1975 Jul 29;14(15):3408-13. doi: 10.1021/bi00686a018.
9
Chemical characterization of acylpolyamine toxins from venom of a trap-door spider and two tarantulas.一种活板门蜘蛛和两种狼蛛毒液中酰基多胺毒素的化学特征分析。
Toxicon. 1990;28(5):541-6. doi: 10.1016/0041-0101(90)90298-l.
10
The venom of the East African spider Pterinochilus sp.东非蜘蛛Pterinochilus sp.的毒液
Toxicon. 1974 May;12(3):303-10. doi: 10.1016/0041-0101(74)90074-9.

引用本文的文献

1
Spider Venom: Components, Modes of Action, and Novel Strategies in Transcriptomic and Proteomic Analyses.蜘蛛毒液：在转录组学和蛋白质组学分析中的成分、作用模式和新策略。
Toxins (Basel). 2019 Oct 22;11(10):611. doi: 10.3390/toxins11100611.
2
Neurotoxic acylpolyamines from spider venoms.来自蜘蛛毒液的神经毒性酰基多胺。
J Chem Ecol. 1993 Oct;19(10):2411-51. doi: 10.1007/BF00979674.