一种活板门蜘蛛和两种狼蛛毒液中酰基多胺毒素的化学特征分析。

Chemical characterization of acylpolyamine toxins from venom of a trap-door spider and two tarantulas.

作者信息

Skinner W S, Dennis P A, Lui A, Carney R L, Quistad G B

机构信息

Sandoz Crop Protection Corporation, Research Division, Palo Alto, CA 94304.

出版信息

Toxicon. 1990;28(5):541-6. doi: 10.1016/0041-0101(90)90298-l.

DOI:10.1016/0041-0101(90)90298-l

PMID:2389254

Abstract

Two acylpolyamines are identified from venom of the trap-door spider, Hebestatis theveniti. These toxins (paralytic to lepidopteran insect larvae) are amides containing 3-(3-indolyl)lactic acid joined to spermine or 1,13-diamino-4,10-diazatridecane (Het389 and Het403, respectively). Het389 is also abundant in venom from a tarantual from Mozambique (Harpactirella sp.). Two additional acylpolyamines (Apc600 and Apc728) are partially characterized from venom of another tarantula, Aphonopelma chalcodes.

摘要

从活板门蛛Hebestatis theveniti的毒液中鉴定出两种酰基多胺。这些毒素（对鳞翅目昆虫幼虫具有麻痹作用）是含有与精胺或1,13-二氨基-4,10-二氮杂十三烷相连的3-(3-吲哚基)乳酸的酰胺（分别为Het389和Het403）。Het389在莫桑比克狼蛛（Harpactirella sp.）的毒液中也很丰富。从另一种狼蛛Aphonopelma chalcodes的毒液中部分鉴定出另外两种酰基多胺（Apc600和Apc728）。