Savage B
Transfusion. 1982 Jul-Aug;22(4):288-91. doi: 10.1046/j.1537-2995.1982.22482251209.x.
Platelet adenine nucleotide levels were measured in freshly prepared platelet concentrates and daily during storage at room temperature. Marked depletions in platelet adenosine triphosphate (ATP) and adenosine diphosphate (ADP) levels were associated with decrease in both plasma glucose levels and poststorage pH. In those concentrates with only moderate glucose consumption, platelet ATP and ADP levels were well preserved and the plasma pH remained above 6.0. The rate of glucose utilization and poststorage pH were greatly influenced by the concentration of contaminating leukocytes. These studies indicate that the rate of exogenous glucose consumption is an important factor affecting platelet adenine nucleotide levels during room temperature storage of platelet concentrates.
在新制备的血小板浓缩物中以及在室温储存期间每天测量血小板腺嘌呤核苷酸水平。血小板三磷酸腺苷（ATP）和二磷酸腺苷（ADP）水平的显著消耗与血浆葡萄糖水平和储存后pH值的降低有关。在那些葡萄糖消耗仅为中等程度的浓缩物中，血小板ATP和ADP水平得到了良好的保存，血浆pH值保持在6.0以上。葡萄糖利用速率和储存后pH值受到污染白细胞浓度的极大影响。这些研究表明，外源性葡萄糖消耗速率是影响血小板浓缩物在室温储存期间血小板腺嘌呤核苷酸水平的一个重要因素。
