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[中国仓鼠与美国水貂体细胞杂种中水貂染色体组的优先保留]

[Preferential retention of the mink chromosome group in somatic cell hybrids of Chinese hamster and American mink].

作者信息

Rubtsov N B, Shverin M, Kulichkov V A, Radzhabli S I

出版信息

Tsitol Genet. 1982 May-Jun;16(3):17-22.

PMID:7101453
Abstract

The chromosomal complement was studied in 57 independent clones of hybrid cells obtained in six experiments for fusion of Chinese hamster and American mink cells. Various mink chromosomes in hybrids of concern are lost. It is shown when a small number of mink chromosomes are retained in hybrid clones, chromosomes 6, 9, 10, 12, 13, 14 and X segregate in a similar way and are preferentially retained in these clones. When a considerable number of mink chromosomes are detained in hybrid clones, the segregation mode is close to a random one.

摘要

对中国仓鼠细胞与美国水貂细胞融合的六个实验中获得的57个杂交细胞独立克隆的染色体组进行了研究。相关杂交细胞中的各种水貂染色体丢失。结果表明,当杂交克隆中保留少量水貂染色体时,6号、9号、10号、12号、13号、14号染色体和X染色体以相似的方式分离,并优先保留在这些克隆中。当杂交克隆中滞留相当数量的水貂染色体时,分离模式接近随机模式。

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