Evdokimova N I, Grigorova T M
Vopr Onkol. 1982;28(7):28-34.
The results of the treatment of 75 patients with ovarian carcinoma of epithelial origin are reported. The authors give a randomised clinical comparison of the efficacy of two schemes of complex treatment of 54 patients with ascitic ovarian carcinoma and 21 patients with non-ascitic ovarian carcinoma. The first scheme included cytoxan chemotherapy plus surgery plus polychemotherapy (25 patients); the second--surgery plus polychemotherapy (29 patients). Patients with non-ascitic carcinoma (21) received the second type of treatment. Polychemotherapy consisted of two alternating schedules: 5 fluorouracil plus cyclophosphamide and hexamethylamine plus cyclophosphamide after a two week interval. Better results were obtained in the group of patients treated surgically at the initial stage of treatment.
报告了75例上皮性卵巢癌患者的治疗结果。作者对54例腹水型卵巢癌和21例非腹水型卵巢癌患者的两种综合治疗方案的疗效进行了随机临床比较。第一种方案包括环磷酰胺化疗加手术加联合化疗（25例患者）；第二种方案——手术加联合化疗（29例患者）。非腹水型癌患者（21例）接受第二种治疗类型。联合化疗由两种交替方案组成：5-氟尿嘧啶加环磷酰胺和六甲蜜胺加环磷酰胺，间隔两周。在治疗初期接受手术治疗的患者组中获得了更好的结果。
