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甲型流感对儿童的影响:一项回顾性研究。

Impact of type A influenza on children: a retrospective study.

作者信息

Mullooly J P, Barker W H

出版信息

Am J Public Health. 1982 Sep;72(9):1008-16. doi: 10.2105/ajph.72.9.1008.

DOI:10.2105/ajph.72.9.1008
PMID:7102849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1650108/
Abstract

Excess morbidity was studied during influenza A epidemics (1968-69, 1972-73) among children in a large prepaid group practice program. Excess rates of hospitalization for influenza-related conditions, primarily pneumonia and bronchitis, ranged from 5 per 10,000 (95 per cent confidence limits (CL): 1 to 9) for non-high-risk children to 29 per 10,000 (95 per cent CL: 5 to 53) for children with high-risk conditions. The relative increases in hospitalization rates were greatest for 5-14 year old boys: 278 per cent and 104 per cent increases for high-risk and non-high-risk boys, respectively. The absolute increase was greatest for 0-4 year olds. The excess rate of ambulatory medical care contacts, 2.6 per 100 (95 per cent CL: -1.6 to 6.8 per 100) was not statistically significant. Excess hospitalization rates among 0-14 year olds during epidemics were three to five times larger than those for persons between 15 and 64 years of age but only one-fifth the rate of persons over age 65.

摘要

在一项大型预付团体医疗服务项目中,对甲型流感流行期间(1968 - 1969年,1972 - 1973年)的儿童超额发病率进行了研究。与流感相关疾病(主要是肺炎和支气管炎)的超额住院率,非高危儿童为每10000人中有5例(95%置信区间(CL):1至9),高危儿童为每10000人中有29例(95% CL:5至53)。住院率的相对增幅在5 - 14岁男孩中最大:高危和非高危男孩分别增加了278%和104%。绝对增幅在0 - 4岁儿童中最大。门诊医疗接触的超额率为每100人中有2.6例(95% CL:每100人 - 1.6至6.8例),无统计学意义。0 - 14岁儿童在流行期间的超额住院率比15 - 64岁人群高3至5倍,但仅为65岁以上人群的五分之一。

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