Ross L A, Finco D R, Crowell W A
Am J Vet Res. 1982 Jun;43(6):1023-6.
Cats with reduced renal mass were fed a phosphorus-restricted diet (0.24% P, dry weight) or a normal phosphorus diet (1.56% P, dry weight) for 6 5 to 343 days. Renal function was determined biweekly by blood urea nitrogen and plasma creatinine measurements and by initial and terminal inulin clearance procedures. Neither diet caused a significant change in renal function during the study. However, histologic examination of kidneys obtained at necropsy clearly separated the cats on the basis of dietary phosphorus. The kidneys from cats fed the normal phosphorus diet had mineralization, fibrosis, and mononuclear cell infiltration, whereas the kidneys from cats fed the phosphorus-restricted diet had little or no changes.
肾质量减少的猫被给予低磷饮食（磷含量0.24%，干重）或正常磷饮食（磷含量1.56%，干重），持续65至343天。每两周通过测量血尿素氮和血浆肌酐以及通过初始和终末菊粉清除程序来测定肾功能。在研究期间，两种饮食均未导致肾功能发生显著变化。然而，尸检时获得的肾脏组织学检查根据饮食中的磷含量将猫明显区分开来。喂食正常磷饮食的猫的肾脏出现矿化、纤维化和单核细胞浸润，而喂食低磷饮食的猫的肾脏几乎没有变化或没有变化。
