Schmidt G M, Krehbiel J D, Coley S C, Leid R W
Am J Vet Res. 1982 Aug;43(8):1371-5.
Equine eyes (368) were examined clinically and histologically for abnormalities associated with the presence of ocular microfilariae of naturally occurring Onchocerca sp infection. Forty of the eyes had microfilariae in the conjunctiva, but distinguishing clinical abnormalities were not associated with their presence. In 1 horse with ocular microfilariae that was treated with diethylcarbamazine daily for 2 weeks, ocular tissue samples were obtained before, during, and after the horse was treated, and the samples were compared histologically. During treatment of the horse, microfilariae apparently moved from the conjunctival stroma into the perilimbal corneal stroma; inflammatory cells were more abundant in the perilimbal tissues. The tissue samples obtained before and after the treatment appeared similar.
对马眼（368只）进行了临床和组织学检查，以查找与自然发生的盘尾丝虫属感染的眼内微丝蚴存在相关的异常情况。40只眼睛的结膜中有微丝蚴，但未发现与微丝蚴存在相关的明显临床异常。对1匹感染眼内微丝蚴的马每天使用乙胺嗪治疗2周，在治疗前、治疗期间和治疗后采集眼部组织样本，并进行组织学比较。在治疗期间，微丝蚴明显从结膜基质移至角膜缘角膜基质；角膜缘组织中的炎性细胞更为丰富。治疗前后采集的组织样本外观相似。
