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部分脂肪营养不良的面部重建

Facial reconstruction in partial lipodystrophy.

作者信息

Hurwitz P J, Sarel R

出版信息

Ann Plast Surg. 1982 Mar;8(3):253-7. doi: 10.1097/00000637-198203000-00018.

DOI:10.1097/00000637-198203000-00018
PMID:7103380
Abstract

Lipodystrophy is a rare disease characterized by progressive disappearance of the subcutaneous fat of the upper part of the body. Accompanying abnormalities of carbohydrate and lipid metabolism, diabetes, nephritis, and low levels of complement are frequent. The most striking clinical features are the extremely hollow cheeks, making the normal facial skeleton rather prominent. Very little has been reported on facial reconstruction in such patients. A 16-year-old girl is presented who was successfully reconstructed after the atrophic process arrested spontaneously. Bilateral dermal fat grafts from the buttocks were used in a one-stage procedure. Nine months later, when no more resorption of fat occurred, some trimming of the grafts was necessary. A good result was achieved.

摘要

脂肪营养不良是一种罕见疾病,其特征为身体上部皮下脂肪进行性消失。常伴有碳水化合物和脂质代谢异常、糖尿病、肾炎以及补体水平降低。最显著的临床特征是脸颊极度凹陷,使正常的面部骨骼显得颇为突出。关于此类患者面部重建的报道极少。本文介绍了一名16岁女孩,其萎缩过程自发停止后成功接受了重建手术。采用一期手术,使用来自臀部的双侧真皮脂肪移植。九个月后,当脂肪不再吸收时,需要对移植组织进行一些修整。取得了良好效果。

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Facial reconstruction in partial lipodystrophy.部分脂肪营养不良的面部重建
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引用本文的文献

1
Clinical Guidance for Lipodystrophy Syndromes: From Diagnosis and Work-Up to Treatment.脂肪代谢障碍综合征的临床指南:从诊断、检查到治疗
Curr Diab Rep. 2025 Sep 2;25(1):47. doi: 10.1007/s11892-025-01603-4.
2
Barraquer Simons Syndrome: Case Series and Review of Surgical Treatments for Facial Lipodystrophy.巴拉奎尔-西蒙斯综合征:面部脂肪营养不良的病例系列及外科治疗综述
Aesthetic Plast Surg. 2025 Mar 24. doi: 10.1007/s00266-025-04794-z.
3
Facial soft tissue volume decreases during metreleptin treatment in patients with partial and generalized lipodystrophy.
在部分和全身性脂肪营养不良患者中, metreleptin 治疗期间面部软组织体积减少。
Endocrine. 2017 Nov;58(2):262-266. doi: 10.1007/s12020-017-1437-8. Epub 2017 Oct 9.
4
The Diagnosis and Management of Lipodystrophy Syndromes: A Multi-Society Practice Guideline.脂肪营养不良综合征的诊断与管理:多学会实践指南
J Clin Endocrinol Metab. 2016 Dec;101(12):4500-4511. doi: 10.1210/jc.2016-2466. Epub 2016 Oct 6.
5
Free dermal fat graft for restoration of soft tissue defects in maxillofacial surgery.游离真皮脂肪移植用于颌面外科软组织缺损的修复
J Maxillofac Oral Surg. 2012 Sep;11(3):319-22. doi: 10.1007/s12663-012-0358-6. Epub 2012 Apr 25.
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Rhytidectomy in patients with facial lipodystrophy: a review of the literature with case presentations.面部脂肪营养不良患者的除皱术:文献综述及病例报告
Aesthetic Plast Surg. 1989 Fall;13(4):267-71. doi: 10.1007/BF01570359.