Sewell D L, Golper T A
Antimicrob Agents Chemother. 1982 Mar;21(3):528-9. doi: 10.1128/AAC.21.3.528.
The stability of cephapirin, gentamicin, penicillin G, nafcillin, ticarcillin, and vancomycin was tested in peritoneal dialysate at 25 degrees C for 24 h. All of the antimicrobial agents were stable except penicillin G, which lost 25% of activity over 24 h (P less than 0.01). The once-daily preparation of drug-dialysate solution is feasible for the treatment of peritonitis in patients on continuous ambulatory peritoneal dialysis.
在25摄氏度下，将头孢匹林、庆大霉素、青霉素G、萘夫西林、替卡西林和万古霉素置于腹膜透析液中测试24小时的稳定性。除青霉素G外，所有抗菌药物均稳定，青霉素G在24小时内活性丧失25%（P<0.01）。对于持续非卧床腹膜透析患者的腹膜炎治疗，每日一次的药物 - 透析液溶液制剂是可行的。
