Dunn E J, Hernandez J, Bender H W, Prager R L
Ann Thorac Surg. 1982 Aug;34(2):176-80. doi: 10.1016/s0003-4975(10)60879-x.
Twenty-one patients who underwent pneumonectomy for bronchogenic carcinoma at the Nashville Veterans Administration Hospital from November, 1977, to March, 1980, were evaluated with standard pulmonary function tests preoperatively and postoperatively. Twelve patients had Stage I disease, 4 patients had Stage II, and 5 patients had Stage III disease. The interval between the operative procedure and postoperative testing ranged from 2 to 33 months (mean, 12.4 months). Mean functional loss of pulmonary capacity after pneumonectomy was based on analysis of preoperative and postoperative forced vital capacity (FVC) and initial-second forced expiratory volume (FEV1) indices. The mean functional loss as expressed by FVC was 41.5% after right pneumonectomy and 34.0% after left pneumonectomy. The mean functional loss as expressed by FEV1 was 40.2% after right pneumonectomy and 38.3% after left pneumonectomy. The postoperative functional status of each patient was classified according to the New York Heart Association criteria. Nineteen of the 21 patients were in Class I or II preoperatively. Postoperatively, 10 patients were in Class I or II and 11 in Class III or IV. The results indicate that a postoperative FVC less than 2.5 liters and FEV1 less than 1.5 liters are not compatible with active life.
1977年11月至1980年3月期间，在纳什维尔退伍军人管理局医院因支气管源性癌接受肺切除术的21例患者，在术前和术后均接受了标准肺功能测试评估。12例患者为I期疾病，4例为II期，5例为III期疾病。手术操作与术后测试之间的间隔时间为2至33个月（平均12.4个月）。肺切除术后肺容量的平均功能损失基于术前和术后用力肺活量（FVC）以及第一秒用力呼气量（FEV1）指数的分析。以FVC表示的平均功能损失在右肺切除术后为41.5%，左肺切除术后为34.0%。以FEV1表示的平均功能损失在右肺切除术后为40.2%，左肺切除术后为38.3%。根据纽约心脏协会标准对每位患者的术后功能状态进行分类。21例患者中有19例术前为I级或II级。术后，10例患者为I级或II级，11例为III级或IV级。结果表明，术后FVC小于2.5升且FEV1小于1.5升与积极生活不相容。
