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A histochemical study of GABA-transaminase in the efferents of the pallidum.

作者信息

Vincent S R, Kimura H, McGeer E G

出版信息

Brain Res. 1982 Jun 3;241(1):162-5. doi: 10.1016/0006-8993(82)91239-2.

DOI:10.1016/0006-8993(82)91239-2
PMID:7104702
Abstract

Kainic acid lesions of the globus pallidus reduce the histochemically detectable GABA-transaminase activity in the ipsilateral subthalamic nucleus. A similar decrease in enzyme activity occurs in the lateral habenula following lesions of the entopeduncular nucleus. Previous results on the localization of GABA-transaminase in efferents of the striatum indicated that such histochemistry may be a useful adjunct for the demonstration of GABA pathways. The present data are consistent with some previous literature indicating that these two pallidal efferents may contain GABA.

摘要

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