Marinier R, Pihl R O, Wilford C, Lapp J
Drug Intell Clin Pharm. 1982 Jul-Aug;16(7-8):556-62. doi: 10.1177/106002808201600705.
Data on patterns of psychotropic drug use from a two-part study of Québec urban women are reported. Part I involved telephone interviews with 1187 women on their use of pain, sleep, and psychotropic medications. In Part II, 179 women participated in a further person-to-person interview. Areas covered included frequency and duration of use, efficacy of the product, dosage, presence of undesirable side effects, source of drug information, and the concomitant use of other medications. Diazepam and flurazepam (Valium and Dalmane) were the most frequently consumed psychotropes, with diazepam second only to aspirin as the most commonly used of all the medications. The majority of psychotropic users obtained the drug initially through a general practitioner for nonspecific health reasons, were satisfied with the efficacy of the drug, took the medication as directed, felt informed of the effects, and found no undesirable side effects. Multiple psychotrope use was not prevalent, and users of mood-modifiers were generally alcohol abstainers. The differences between the high and moderate users, including satisfaction with the psychotropes as well as initial dosages, are discussed along with comparative data from other similar drug studies. Findings lend credence to the hypothesis that the vague and ill-defined health problems precipitating a psychotropic prescription may in fact be economic, social, or psychological in origin.
报告了一项针对魁北克城市女性的两部分研究中有关精神药物使用模式的数据。第一部分涉及对1187名女性进行电话访谈，了解她们使用止痛、助眠和精神药物的情况。在第二部分中，179名女性参与了进一步的面对面访谈。涵盖的领域包括使用频率和持续时间、产品疗效、剂量、不良副作用的存在、药物信息来源以及其他药物的同时使用情况。地西泮和氟西泮（安定和氟胺安定）是最常使用的精神药物，地西泮是所有药物中仅次于阿司匹林的最常用药物。大多数精神药物使用者最初是因非特定健康原因通过全科医生获得药物的，对药物疗效满意，按指示服药，了解药物效果，且未发现不良副作用。多种精神药物联合使用并不普遍，使用情绪调节药物的使用者通常戒酒。文中讨论了高剂量使用者和中等剂量使用者之间的差异，包括对精神药物的满意度以及初始剂量，并与其他类似药物研究的比较数据进行了对比。研究结果支持了这样一种假设，即促成精神药物处方的模糊且定义不明确的健康问题实际上可能源于经济、社会或心理因素。
