Ohayon M M, Caulet M, Priest R G, Guilleminault C
Centre de Recherche Philippe Pinel de Montréal, Québec, Canada.
J Clin Epidemiol. 1998 Mar;51(3):273-83. doi: 10.1016/s0895-4356(97)00238-2.
The prevalence of psychotropic medication consumption was assessed in the UK by surveying a representative sample of 4972 non-institutionalized individuals 15 years of age or older (participation rate, 79.6%). A questionnaire was administered over the telephone with the help of the Sleep-Eval Expert System. Topics covered included: type and name of medication, indication, dosage, duration of intake, and medical specialty of prescriber. Also collected were data pertaining to sociodemographics, physical illnesses, and DSM-IV mental disorders. Overall, 3.5% [95% CI: 3-4] of the sample reported current use of psychotropic medication. Consumption was higher among women [4.6% (3.8-5.4)] than men [2.3% (1.7-2.9)], and among the elderly (> or = 65 years of age). The distribution of psychotropics was: hypnotics 1.5%, antidepressants 1.1%, and anxiolytics 0.8%. The median duration of psychotropic intake was 52 weeks. General practitioners were the most common prescribers of psychotropics (over 80% for each class of drug). Nearly half the antidepressant users were diagnosed by the system with a DSM-IV anxiety disorder, and one-fifth the anxiolytic users with a depressive disorder. A marked improvement in sleep quality was reported by half the subjects using a psychotropic for sleep-enhancing purposes. Psychotropic users were more likely than non-users to report episodes of memory loss, vertigo, or anomia. Psychotropic medication consumption is lower and patterns of psychotropic prescription differ in the UK compared with other European and North American countries. Results suggest that physicians may not be sufficiently trained to deal with the overlap between general practice and psychiatry.
通过对4972名15岁及以上非住院个体的代表性样本进行调查(参与率为79.6%),评估了英国精神药物的消费情况。借助睡眠评估专家系统通过电话进行问卷调查。涵盖的主题包括:药物类型和名称、适应症、剂量、摄入持续时间以及开处方医生的医学专业。还收集了有关社会人口统计学、身体疾病和DSM-IV精神障碍的数据。总体而言,3.5%[95%置信区间:3 - 4]的样本报告目前正在使用精神药物。女性[4.6%(3.8 - 5.4)]的消费量高于男性[2.3%(1.7 - 2.9)],老年人(≥65岁)的消费量也较高。精神药物的分布情况为:催眠药1.5%,抗抑郁药1.1%,抗焦虑药0.8%。精神药物摄入的中位持续时间为52周。全科医生是最常见的精神药物开处方者(每类药物超过80%)。近一半的抗抑郁药使用者被该系统诊断为患有DSM-IV焦虑症,五分之一的抗焦虑药使用者患有抑郁症。使用精神药物用于改善睡眠的受试者中有一半报告睡眠质量有明显改善。与未使用者相比,精神药物使用者更有可能报告记忆力丧失、眩晕或命名障碍发作。与其他欧洲和北美国家相比,英国的精神药物消费量较低,精神药物处方模式也有所不同。结果表明,医生可能没有得到足够的培训来处理全科医疗和精神病学之间的重叠问题。