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[肠上皮细胞吸收周期的细胞生理学]

[Cytophysiology of the absorption cycle of enterocytes].

作者信息

Iuldashev A Iu, Parpiev A P, Khalelov I, Saliev N Sh

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1978 Sep;64(9):1240-4.

PMID:710629
Abstract

The protein absorption (albumin and gamma-globulin) by epithelial cells of small intestine of neonatal rats was studied in order to define the duration of its stages, the role of intracellular structures in trensport of the absorbed substances, and the cyclic activity of enterocytes. The volume of the absorbed substances depends on the number and size of pynocytotic formations at the cell apex. The protein transport via cells into interstitia is an active process involving the Golgi complex, mitochondria, and other cellular structures. Due to be intracellular regeneration, the restoration of enterocytes begins from gradual protein unloading and is over when the product has been transported to the lymphatic capillary lumen from interstitia. As a result, the continuous absorption is possible in the mucous layer of small intestine although the villi enterocytes activity is of a cyclic character.

摘要

为了确定新生大鼠小肠上皮细胞蛋白质吸收(白蛋白和γ-球蛋白)各阶段的持续时间、细胞内结构在吸收物质转运中的作用以及肠上皮细胞的周期性活动,对其进行了研究。吸收物质的量取决于细胞顶端胞饮结构的数量和大小。蛋白质通过细胞转运到间质是一个涉及高尔基体、线粒体和其他细胞结构的活跃过程。由于细胞内的再生作用,肠上皮细胞的恢复始于蛋白质的逐渐卸载,并在产物从间质转运到淋巴毛细管腔时结束。因此,尽管绒毛肠上皮细胞的活动具有周期性,但小肠黏膜层仍可实现持续吸收。

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