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一项关于人类间皮瘤的研究。

Studies of a human mesothelioma.

作者信息

Behbehani A M, Hunter W J, Chapman A L, Lin F

出版信息

Hum Pathol. 1982 Sep;13(9):862-6. doi: 10.1016/s0046-8177(82)80083-x.

Abstract

Abdominal fluid from a patient with mesothelioma was cultured in vitro, and a cell line designated JMN was established. This cell line has undergone more than 100 passages. Electron microscopic, karyotypic, and heterotransplantation studies as well as the capability of collagen synthesis by this cell line indicated that it is of malignant mesothelial origin. The cell line has proved very useful for the isolation of human pathogenic viruses.

摘要

对一名间皮瘤患者的腹腔积液进行体外培养,建立了一个名为JMN的细胞系。该细胞系已传代100多次。电子显微镜、核型和异种移植研究以及该细胞系的胶原蛋白合成能力表明,它起源于恶性间皮。该细胞系已被证明对分离人类致病病毒非常有用。

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