Bosello O, Armellini F, Pelloso M, Ostuzzi R, Ottolenghi A, Scuro L A
Diabete Metab. 1978 Sep;4(3):159-62.
Twelve patients with body weight varying from 106 to 163 Kg, underwent jejunoileal bypass operations; their oral glucose tolerance tests (oGTT) were evaluated before the operation and one, five, and fifteen months afterwards. The lowering of the glycemic curve and the decrease of the insulinemia values during oGTT have been studied in relation to intestinal absorption deficit and weight loss. It is concluded that weight loss was the main factor determining the improvement of glucose metabolism.
12名体重在106至163千克之间的患者接受了空肠回肠分流手术;在手术前以及术后1个月、5个月和15个月对他们进行了口服葡萄糖耐量试验(oGTT)评估。研究了oGTT期间血糖曲线的降低和胰岛素血症值的下降与肠道吸收缺陷和体重减轻的关系。得出的结论是,体重减轻是决定葡萄糖代谢改善的主要因素。