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小鼠对草花粉的超敏反应

Grass pollen hypersensitivity in mice.

作者信息

McCaskill A C, Hosking C S, Hill D J

出版信息

Immunology. 1982 Aug;46(4):745-50.

PMID:7106842
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1555486/
Abstract

Mice were sensitized by intranasal administration of ryegrass pollen. Subsequent nasal challenge with pollen extract led to a `shock' response peaking in severity 4 hr after challenge. Histological examination of lungs revealed the development of a pneumonitis which was most severe 3 days after challenge.

摘要

通过鼻内给予黑麦草花粉使小鼠致敏。随后用花粉提取物进行鼻腔激发，导致“休克”反应，在激发后4小时严重程度达到峰值。对肺部进行组织学检查发现，激发后3天出现最严重的肺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16a/1555486/2165c4ecf23a/immunology00229-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16a/1555486/2165c4ecf23a/immunology00229-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16a/1555486/2165c4ecf23a/immunology00229-0071-a.jpg

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本文引用的文献

1
MECHANISM OF ANAPHYLACTIC DEATH IN THE MOUSE.小鼠过敏性死亡的机制
Nature. 1965 Jan 9;205:199-200. doi: 10.1038/205199b0.
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Zymosan-induced experimental hypersensitivity pneumonitis in rabbits.酵母聚糖诱导的兔实验性过敏性肺炎
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3
Ige antibody formation in BALB/c mice without adjuvant: induction of responses to grass pollen extract and to a hapten-carrier conjugate.无佐剂情况下BALB/c小鼠中IgE抗体的形成：对草花粉提取物和半抗原-载体偶联物反应的诱导
Immunology. 1980 Apr;39(4):583-8.
4
A study of the rat passive cutaneous anaphylaxis (PCA) reaction for the assay of mouse IgE antibody.一项用于检测小鼠IgE抗体的大鼠被动皮肤过敏反应（PCA）研究。
J Immunol Methods. 1980;33(4):369-77. doi: 10.1016/0022-1759(80)90006-x.
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Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen.通过预先吸入抗原抑制小鼠体内特异性IgE反应。
Immunology. 1981 Mar;42(3):409-17.
6
IgE and haemagglutinating antibody production in mice following intranasal immunization with ryegrass pollen.用黑麦草花粉经鼻内免疫后小鼠体内IgE和血凝抗体的产生
Int Arch Allergy Appl Immunol. 1982;67(2):191-3. doi: 10.1159/000233014.
7
Animal models of the asthmatic state.哮喘状态的动物模型。
Annu Rev Med. 1974;25(0):53-68. doi: 10.1146/annurev.me.25.020174.000413.
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Effect of combinations of inbred strain, antigen, and antigen dose on immune responsiveness and reagin production in the mouse. A potential mouse model for immune aspects of human atopic allergy.近交系、抗原及抗原剂量组合对小鼠免疫反应性和反应素产生的影响。一种人类特应性过敏免疫方面的潜在小鼠模型。
Int Arch Allergy Appl Immunol. 1970;39(2-3):156-71. doi: 10.1159/000230343.
9
Studies on immune responses to parasite antigens in mice. II. Aspects of the T cell dependence of circulating reagin production to Ascaris suum antigens.小鼠对寄生虫抗原免疫反应的研究。II. 循环反应素产生对猪蛔虫抗原的T细胞依赖性方面。
Int Arch Allergy Appl Immunol. 1976;52(1-4):79-94. doi: 10.1159/000231670.
10
Sensitivity to intravenous injections of histamine and serotonin in inbred mouse strains.近交系小鼠品系对静脉注射组胺和5-羟色胺的敏感性。
Int Arch Allergy Appl Immunol. 1977;53(6):545-54. doi: 10.1159/000231796.