用黑麦草花粉经鼻内免疫后小鼠体内IgE和血凝抗体的产生
IgE and haemagglutinating antibody production in mice following intranasal immunization with ryegrass pollen.
作者信息
McCaskill A C, Hosking C S, Hill D J
出版信息
Int Arch Allergy Appl Immunol. 1982;67(2):191-3. doi: 10.1159/000233014.
PMID:7056597
Abstract
Repeated intranasal immunization of mice whole ryegrass pollen (RGP) led to the development of high circulating titres of both IgE and haemagglutinating antibodies. Bordetella pertussis vaccine (BPV) was required at the time of initial immunization, although its repeated use did not affect IgE production. Antibody production was maintained at high levels for greater than 4 months. Significant differences were found in the ability of different batches and strains of BPV to induce production.
摘要
对小鼠反复进行全黑麦草花粉（RGP）鼻内免疫，导致循环中IgE和血凝抗体的高滴度产生。初次免疫时需要百日咳博德特氏菌疫苗（BPV），尽管重复使用它并不影响IgE的产生。抗体产生在4个月以上维持在高水平。发现不同批次和菌株的BPV诱导产生抗体的能力存在显著差异。
相似文献
1
IgE and haemagglutinating antibody production in mice following intranasal immunization with ryegrass pollen.用黑麦草花粉经鼻内免疫后小鼠体内IgE和血凝抗体的产生
Int Arch Allergy Appl Immunol. 1982;67(2):191-3. doi: 10.1159/000233014.
2
Inhibition of murine reaginic antibody responses by nasal immunotherapy with modified allergen.用改良变应原进行鼻腔免疫疗法对小鼠反应素抗体应答的抑制作用
Int Arch Allergy Appl Immunol. 1980;62(4):382-8. doi: 10.1159/000232540.
3
Mucosal and systemic antibody responses against an acellular pertussis vaccine in mice after intranasal co-administration with recombinant cholera toxin B subunit as an adjuvant.鼻内联合使用重组霍乱毒素B亚单位作为佐剂后，小鼠针对无细胞百日咳疫苗的黏膜和全身抗体反应。
Vaccine. 2003 Mar 7;21(11-12):1165-73. doi: 10.1016/s0264-410x(02)00516-9.
4
Effects of Bordetella pertussis components on IgE and IgG1 responses.
Microbiol Immunol. 1983;27(11):905-15. doi: 10.1111/j.1348-0421.1983.tb00656.x.
5
Boosterable IgE antibody response in mice without the use of adjuvant.
Int Arch Allergy Appl Immunol. 1982;67(1):96-8. doi: 10.1159/000232995.
6
Grass conjuvac. I. Immunogenicity in rabbits, guinea pigs and rats.青草联合疫苗I. 对兔、豚鼠和大鼠的免疫原性
Int Arch Allergy Appl Immunol. 1983;72(1):79-83.
7
Rat IgE production. I. Effect of dose of antigen on primary and secondary reaginic antibody responses.大鼠IgE的产生。I. 抗原剂量对初次和再次反应素抗体应答的影响。
Immunology. 1974 Sep;27(3):365-81.
8
Differential suppressive influence of intranasal application of rye grass pollen extract on IgE antibody production in the mouse.鼻内应用黑麦草花粉提取物对小鼠IgE抗体产生的差异性抑制作用。
Clin Exp Immunol. 1985 Feb;59(2):343-50.
9
Production of circulating reaginic (IgE) antibodies by oral administration of ovalbumin to rats.通过向大鼠口服卵清蛋白产生循环反应素（IgE）抗体。
Immunology. 1976 May;30(5):679-84.
10
The non-specific enhancement of allergy. I. In vivo effects of Bordetella pertussis vaccine on IgE synthesis.过敏的非特异性增强作用。I. 百日咳博德特氏菌疫苗对IgE合成的体内效应
Allergy. 1983 May;38(4):239-46. doi: 10.1111/j.1398-9995.1983.tb01617.x.
引用本文的文献
1
Grass pollen hypersensitivity in mice.小鼠对草花粉的超敏反应
Immunology. 1982 Aug;46(4):745-50.
2
Differential suppressive influence of intranasal application of rye grass pollen extract on IgE antibody production in the mouse.鼻内应用黑麦草花粉提取物对小鼠IgE抗体产生的差异性抑制作用。
Clin Exp Immunol. 1985 Feb;59(2):343-50.
Zotero 插件