Bilateral oophorectomy and plasma renin substrate concentration.
作者信息
Immonen I, Lammintausta R, Fyhrquist F, Erkkola R, Punnonen R, Rauramo L
出版信息
Int J Clin Pharmacol Ther Toxicol. 1982 Jun;20(6):287-8.
PMID:7107078
Abstract
Plasma renin substrate concentration was studied in 11 premenopausal women subjected to bilateral oophorectomy and hysterectomy. Preoperative plasma renin substrate concentration was 1573 +/- 477 ng angiotensin I/ml (mean +/- SD). Plasma renin substrate concentration did not change significantly after operation (1632 +/- 459 ng angiotensin I/ml) or after 3 months of postoperative estradiol valerate treatment (2 mg/day) (1762 +2- 467 ng angiotensin I/ml). It is concluded that non-pregnant levels of endogenous estrogens are of no significance in the regulation of plasma renin substrate.
摘要
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