Martin M V, Lamb D J
J Clin Pathol. 1982 Aug;35(8):888-91. doi: 10.1136/jcp.35.8.888.
A comparison has been made between the serotypes of oral Candida albicans taken from patients with denture-induced stomatitis and from a group of age and sex-matched controls. C albicans isolates were obtained from the fitting surface of the denture, the palatal mucosa supporting the denture, and the buccal mucosa. Twenty-nine of the 30 patients samples in the group affected by denture-induced stomatitis had only C albicans serotype A on their palatal mucosa and denture surface, while mixtures of serotypes were obtained from the buccal mucosa of these patients. Only one patient had serotype B isolates from the palatal mucosa and denture surface. In contrast, the control group had mixture of A and B serotypes from both the denture surface and the palatal mucosa, as well as from the buccal sites sampled. It would appear from these results that denture-induced stomatitis is associated with the proliferation of a single C albicans serotype, usually serotype A.
对取自义齿性口炎患者以及年龄和性别匹配的对照组的口腔白色念珠菌血清型进行了比较。白色念珠菌分离株取自义齿的贴合面、支撑义齿的腭黏膜以及颊黏膜。在受义齿性口炎影响的组中,30例患者样本中有29例在其腭黏膜和义齿表面仅存在白色念珠菌血清型A,而从这些患者的颊黏膜中获得了血清型混合物。只有1例患者在腭黏膜和义齿表面分离出血清型B。相比之下,对照组在义齿表面、腭黏膜以及所采样的颊部部位均有A和B血清型的混合物。从这些结果来看,义齿性口炎与单一白色念珠菌血清型(通常为血清型A)的增殖有关。