Ruelland A, Mention J E, Perrot Y, Cloarec L
J Gynecol Obstet Biol Reprod (Paris). 1982;11(2):241-4.
As liquor contains only HDL (High Density Lipoprotein) as a lipoprotein we have studied the changes in the levels of apolipoprotein A, which is the major component of HDL according to the duration of the pregnancy. The study has been carried out in normal and pathological pregnancies. It has been found that the level of apolipoprotein A rises from the 16th week of amenorrhoea of pregnancy to the 26th week and then gradually drops to term. The maximum level is approximately ten times greater than the level of apolipoprotein A at term (a level approximately of 1 mg per litre). This change parallels that of total proteins throughout pregnancy. We have limited our study in pathological pregnancies to the examination of the liquor at the end of pregnancy. The three pathological maternal conditions that have been most frequently found are:--diabetes,--Rhesus-immunisation,--vasculo-renal syndromes. There has been no significant change shown up in the period that we have studied, which was from the 30th to the 38th week of amenorrhoea.
由于羊水仅含有高密度脂蛋白（HDL）作为脂蛋白，我们根据孕期时长研究了载脂蛋白A水平的变化，载脂蛋白A是HDL的主要成分。该研究在正常和病理妊娠中进行。研究发现，载脂蛋白A水平从妊娠闭经第16周升至第26周，然后逐渐降至足月。最高水平约为足月时载脂蛋白A水平的十倍（足月时水平约为每升1毫克）。这种变化与整个孕期总蛋白的变化相似。我们将病理妊娠的研究局限于妊娠末期羊水的检查。最常发现的三种病理母体情况是：——糖尿病，——恒河猴免疫，——血管-肾综合征。在我们研究的闭经第30至38周期间，未显示出显著变化。
