Stoll B J, Glass R I, Huq M I, Khan M U, Banu H, Holt J
J Infect Dis. 1982 Aug;146(2):177-83. doi: 10.1093/infdis/146.2.177.
The epidemiologic and clinical characteristics of 412 patients infected with Shigella from a systematic sample of approximately 100,000 patients attending Dacca Hospital, International Centre for Diarrhoeal Disease Research, Bangladesh, between December 1, 1979, and November 30, 1980, were reviewed. Shigella was isolated from 11.6% of the 3,550 patients in the sample and was the second most common isolate in patients over two years old. Two clinical presentations of shigellosis were found: (I) watery diarrhea occurring in younger children and associated with a shorter duration of illness and with more vomiting and dehydration and (2) dysentery with stool blood and abdominal pain. These different presentations may reflect two mechanisms in the pathogenesis of shigellosis or different stages of the disease. The most useful signs and symptoms for the diagnosis of shigellosis were stool with blood and abdominal pain in all patients and the absence of watery diarrhea and vomiting in patients over one year old. Simple visual inspection of stool for blood correctly identified 44% of all patients infected with Shigella.
对1979年12月1日至1980年11月30日期间在孟加拉国达卡医院国际腹泻病研究中心就诊的约100,000名患者的系统样本中412例感染志贺氏菌的患者的流行病学和临床特征进行了回顾。在样本中的3550名患者中，11.6%分离出志贺氏菌，在两岁以上患者中是第二常见的分离菌。发现了志贺氏菌病的两种临床表现：（1）幼儿出现水样腹泻，病程较短，呕吐和脱水较多；（2）痢疾伴有便血和腹痛。这些不同的表现可能反映了志贺氏菌病发病机制中的两种机制或疾病的不同阶段。诊断志贺氏菌病最有用的体征和症状是所有患者的便血和腹痛，以及一岁以上患者无水样腹泻和呕吐。简单地肉眼观察粪便中的血液可正确识别44%的所有感染志贺氏菌的患者。
