James D G, Barter S, Jash D, MacKinnon D M, Carstairs L S
J Laryngol Otol. 1982 Aug;96(8):711-8. doi: 10.1017/s0022215100093026.
A series of eight hundred and eighteen patients with histologically-confirmed multisystem sarcoidosis was analysed; within this series were 53 (6 per cent) patients with sarcoidosis of the upper respiratory tract (SURT). Two-thirds presented with predominantly upper respiratory tract symptoms when the systemic disorder was minimal or unrecognized. Women were affected twice as often as men. SURT is commonly associated with lupus pernio and other manifestations of chronic fibrotic sarcoidosis, and it follows the same indolent course. When granulomas are found on biopsy of the upper respiratory tract, there should be a management plan to determine whether they are due to multisystem sarcoidosis or other granulomatous disorders including tuberculosis, Wegener's granulomatosis and leprosy. About one-half of patients with SURT will need oral steroids, either alone or in combination with topical steroids or chloroquine.
对818例经组织学确诊的多系统结节病患者进行了分析；在该系列中，有53例（6%）上呼吸道结节病（SURT）患者。三分之二的患者在全身疾病轻微或未被识别时主要表现为上呼吸道症状。女性受影响的频率是男性的两倍。SURT通常与冻疮样狼疮和慢性纤维化结节病的其他表现相关，并且病程相同。当上呼吸道活检发现肉芽肿时，应有一个管理计划来确定它们是否由多系统结节病或其他肉芽肿性疾病引起，包括结核病、韦格纳肉芽肿病和麻风病。约一半的SURT患者需要单独或联合局部使用类固醇或氯喹口服类固醇。
