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发育中的鸡腿部骨骼部分的近端到远端的决定

The proximodistal determination of skeletal parts in the developing chick leg.

作者信息

Rowe D A, Fallon J F

出版信息

J Embryol Exp Morphol. 1982 Apr;68:1-7.

PMID:7108415
Abstract

Currently the chick leg bud or its components are being used extensively to study questions in development. Although fate maps of the leg, similar to that developed by Saunders (1948) for the wing, have been available (Hampé, 1957 a, 1959), no study of the proximodistal sequence of the specification of leg structures exists. Such a sequence developed for the wing by removal of the apical ectodermal ridge at successive stages (Saunders, 1948; Summerbell, 1974), has proven useful to the study of wing development. In this paper, we present a similar proximodistal sequence for the chick leg including the same developmental stage range as that of the wing sequence.

摘要

目前,鸡的腿芽或其组成部分正被广泛用于研究发育问题。尽管腿部的命运图谱,类似于桑德斯(1948年)为翅膀绘制的图谱,已经存在(汉佩,1957年a,1959年),但尚未有关于腿部结构指定的近端到远端序列的研究。通过在连续阶段去除顶端外胚层嵴为翅膀建立的这样一个序列(桑德斯,1948年;萨默贝尔,1974年),已被证明对翅膀发育的研究很有用。在本文中,我们给出了鸡腿部类似的近端到远端序列,包括与翅膀序列相同的发育阶段范围。

相似文献

1
The proximodistal determination of skeletal parts in the developing chick leg.发育中的鸡腿部骨骼部分的近端到远端的决定
J Embryol Exp Morphol. 1982 Apr;68:1-7.
2
Development of the apical ectodermal ridge in the chick leg bud and a comparison with the wing bud.鸡胚腿芽顶端外胚层嵴的发育及其与翼芽的比较。
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Development of the apical ectodermal ridge in the chick wing bud.鸡翼芽中顶端外胚层嵴的发育。
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Lack of correlation between mesenchymal cell death and morphogenesis after different extents of apical ectodermal ridge/rim ectoderm removal in the chick embryo wing bud.鸡胚翅芽不同程度去除顶端外胚层嵴/边缘外胚层后间充质细胞死亡与形态发生之间缺乏相关性。
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In vivo inhibition of programmed cell death by local administration of FGF-2 and FGF-4 in the interdigital areas of the embryonic chick leg bud.通过在胚胎鸡腿部芽的趾间区域局部施用FGF-2和FGF-4对程序性细胞死亡进行体内抑制。
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Formation of extra digits in the interdigital spaces of the chick leg bud is not preceded by changes in the expression of the Msx and Hoxd genes.鸡胚腿芽指间区域额外趾的形成并非先于Msx和Hoxd基因表达的变化。
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Formation of extra-digits induced by surgical removal of the apical ectodermal ridge of the chick embryo leg bud in the stages previous to the onset of interdigital cell death.在趾间细胞死亡开始之前的阶段,通过手术切除鸡胚腿芽的顶端外胚层嵴诱导额外趾的形成。
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