棕榈酸对冷适应和热适应大鼠骨骼肌线粒体的影响。
The effects of palmitic acid on skeletal muscle mitochondria of cold and warm acclimated rats.
作者信息
Ballantyne J S, George J C
出版信息
Arch Int Physiol Biochim. 1977 Apr;85(2):281-6. doi: 10.3109/13813457709058760.
PMID:71086
Abstract
The effects of palmitic acid on skeletal muscle mitochondria isolated from the hind limb muscle of cold and warm acclimated rats were studied. At higher concentrations of the fatty acid, a greater depression of both ADP/O and RCR (respiratory control ratio) was observed in the cold acclimated group. Initial ADP/O and RCC however, were higher in the cold acclimated group. The enhanced sensitivity of skeletal muscle mitochondria of the cold acclimated rat is discussed.
摘要
研究了棕榈酸对从冷适应和热适应大鼠后肢肌肉分离出的骨骼肌线粒体的影响。在较高脂肪酸浓度下，冷适应组的ADP/O和RCR（呼吸控制率）下降幅度更大。然而，冷适应组的初始ADP/O和RCC较高。文中讨论了冷适应大鼠骨骼肌线粒体敏感性增强的现象。
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