Schumpelick V, Massarwa O, Schreiber H W
Langenbecks Arch Chir. 1982;357(2):93-103. doi: 10.1007/BF01237455.
A retrospective study was made based on 243 patients with simple closure of a perforated peptic ulcer in order to analyse factors influencing the results. Complications and mortality showed a good correlation with age, time between onset of symptoms and operation and size of the perforation, but no correlation with ulcer localization and history. Between 1 and 15 years after the operation, 39,4% of the patients were asymptomatic, 34,8% under conservative treatment, whilst 25,8% had to be reoperated on in the meantime. There was no correlation between recurrence and the age of the patients, the time between onset of symptoms and operation, the duration of stay in hospital, inability to work, alcohol and nicotine abuse. Ulcer history was the only factor influencing the late result significantly. Only 11% of patients with a short ulcer history (no longer than 6 months) had to be reoperated on whereas in those with a long ulcer history a recurrence rate of 70% can be expected. The importance of ulcer history for the choice of surgical treatment is emphasized.
对243例单纯性消化性溃疡穿孔闭合患者进行了回顾性研究,以分析影响治疗结果的因素。并发症和死亡率与年龄、症状出现至手术的时间以及穿孔大小密切相关,但与溃疡部位和病史无关。术后1至15年间,39.4%的患者无症状,34.8%接受保守治疗,而25.8%在此期间必须再次手术。复发与患者年龄、症状出现至手术的时间、住院时间、无法工作、酗酒和吸烟无关。溃疡病史是唯一显著影响远期结果的因素。溃疡病史短(不超过6个月)的患者中只有11%需要再次手术,而溃疡病史长的患者复发率预计为70%。强调了溃疡病史对手术治疗选择的重要性。