Kuroki M, Kameyama S, Toyama M, Watanabe M, Kurokawa I
No Shinkei Geka. 1982 May;10(5):541-6.
Three cases of neuroblastoma with intracranial metastases were reported. The first case was a 13-year-old girl with sacral neuroblastoma who had metastases to the left parietal bone and dura, and had bilateral intraorbital metastases. The second case was a 13-year-old girl with mediastinal neuroblastoma who had bilateral intraorbital metastases. The third case was a 49-year-old woman with esthesioneuroblastoma which had invaded to the dura at the right middle fossa and the right orbit. CT findings of the brain of these three cases were investigated, and summarized as follows: 1) The intracranial invasions of the metastatic tumors were seen to be slightly high density (EMI-number 25-27) in plain scans, and homogeneously enhanced as a well-defined high density mass (EMI-number 35-37). 2) The tumors invading the skull were observed as a mass lesion of the bone on osteolytic lesion. 3) The intraorbital metastatic tumors were seated on the orbital wall invading the rectal muscles, but they remained extraconal. It was emphasized that CT could give valuable information for the diagnosis of skull and intracranial metastasis of neuroblastoma.
报告了3例神经母细胞瘤颅内转移病例。第一例是一名13岁女孩，患有骶骨神经母细胞瘤，已转移至左顶骨和硬脑膜，并伴有双侧眶内转移。第二例是一名13岁女孩，患有纵隔神经母细胞瘤，伴有双侧眶内转移。第三例是一名49岁女性，患有嗅神经母细胞瘤，已侵犯右中颅窝硬脑膜和右侧眼眶。对这3例患者的脑部CT表现进行了研究，总结如下：1）转移性肿瘤的颅内侵犯在平扫时表现为略高密度（EMI值25 - 27），增强扫描时呈均匀强化的边界清晰的高密度肿块（EMI值35 - 37）。2）侵犯颅骨的肿瘤在溶骨性病变处表现为骨质的肿块病变。3）眶内转移性肿瘤位于眶壁，侵犯眼外肌，但仍位于肌锥外。强调CT可为神经母细胞瘤颅骨及颅内转移的诊断提供有价值的信息。
