Zimmerman R A, Bilaniuk L T
AJR Am J Roentgenol. 1980 Dec;135(6):1239-42. doi: 10.2214/ajr.135.6.1239.
Eleven children with craniocerebral neuroblastoma (three primary and eight metastatic) were examined by computed tomography (CT). The findings in both primary and secondary neuroblastoma correlate well with the known neuropathologic findings. Primary cerebral neuroblastoma originates in the brain parenchyma of the supratentorial space, and may extend into the cerebrospinal fluid pathways. Secondary neuroblastoma is confined to the osseous structures of the calvarium and orbit, and adjacent subperiosteal spaces (epidural and epicranial). In both forms of neuroblastoma, intratumoral hemorrhage is frequent. Separation of the cranial sutures often relates to epidural deposits of tumor extending to the sutural margins. In this form of sutural diastasis, intracranial pressure is not elevated. When elevated intracranial pressure accompanies sutural diastatis, CT findings reveal epidural deposits compressing the major dural venous sinuses in the region of their confluence.
对11例颅神经母细胞瘤患儿（3例原发性和8例转移性）进行了计算机断层扫描（CT）检查。原发性和继发性神经母细胞瘤的检查结果与已知的神经病理学结果密切相关。原发性脑神经母细胞瘤起源于幕上空间的脑实质，并可能延伸至脑脊液通路。继发性神经母细胞瘤局限于颅盖骨和眼眶的骨质结构以及相邻的骨膜下间隙（硬膜外和颅顶）。在这两种神经母细胞瘤中，肿瘤内出血都很常见。颅骨缝的分离通常与肿瘤延伸至缝缘的硬膜外沉积有关。在这种形式的缝间骨分离中，颅内压并未升高。当颅内压升高伴随缝间骨分离时，CT检查结果显示硬膜外沉积物在其汇合区域压迫主要的硬脑膜静脉窦。
