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[核磁共振。在医学和生物学中的应用(作者译)]

[Nuclear magnetic resonance. Applications to medicine and biology (author's transl)].

作者信息

Berdugo M, Fauchet M, Menasche P, Grall Y, Piwnica P

出版信息

Nouv Presse Med. 1982 Jun 19;11(29):2215-8.

PMID:7110983
Abstract

Nuclear magnetic resonance (NMR) is a non-invasive exploratory technique based on a principle radically different from those of radiography, radionuclide exploration and ultrasonography. Signals coming from atomic nuclei and reflecting their density and chemical/biochemical environment are collected, thus providing information of the physiological and pathological state of tissues. The technique has multiple applications, either practical (tomographic imaging of the brain, thyroid gland and liver) or in the field of research, e.g. investigating ischaemic myocardial areas and pathological fluid composition, measuring intracellular pH, diagnosing the nature of a tumour and, broadly speaking, understanding the biochemical changes associated with malignant degeneration.

摘要

核磁共振(NMR)是一种非侵入性的探测技术,其原理与放射照相、放射性核素探测及超声检查完全不同。该技术收集来自原子核的信号,这些信号反映了原子核的密度及其化学/生物化学环境,从而提供有关组织生理和病理状态的信息。这项技术有多种应用,既包括实际应用(如脑部、甲状腺和肝脏的断层成像),也包括研究领域的应用,例如研究心肌缺血区域和病理性液体成分、测量细胞内pH值、诊断肿瘤的性质,广义而言,还包括了解与恶性病变相关的生化变化。

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