Chatterji J C, Ohri V C, Das B K, Chadha K S, Akhtar M, Bhatacharji P, Tewari S C, Behl A
Thromb Res. 1982 May 1;26(3):177-82. doi: 10.1016/0049-3848(82)90138-4.
Two groups of 20 subjects each were separately exposed to altitudes of 3200 m and 3771 m for 10 days by rapid induction requiring 14 and 16 hours respectively to reach high altitude camps. A statistically significant fall in platelet counts was observed from day 2 at 3200 m and day 3 at 3771 m and counts remained decreased. Platelet aggregation was also decreased initially at both altitudes. Blood fibrinogen decreased only on day 2 at 3771 m with a significant increase over control values by day 10 at both altitudes.
两组,每组20名受试者,分别通过快速诱导暴露于海拔3200米和3771米的高度,分别需要14小时和16小时到达高海拔营地,持续10天。在海拔3200米处从第2天起以及在海拔3771米处从第3天起观察到血小板计数有统计学意义的下降,且计数持续降低。在两个海拔高度处,血小板聚集最初也有所下降。仅在海拔3771米处的第2天血液纤维蛋白原有所下降,在两个海拔高度处到第10天时均显著高于对照值。