葡萄球菌α毒素与离体兔迷走神经的体外特异性结合。
Specific binding of staphylococcal alpha-toxin to isolated rabbit vagus nerves in vitro.
作者信息
Szmigielski S, Harshman S
出版信息
Infect Immun. 1978 Sep;21(3):1024-6. doi: 10.1128/iai.21.3.1024-1026.1978.
Abstract
The binding of staphylococcal [125I]alpha-toxin to rabbit vagus nerves in vitro was a saturable process. The radiolabeled alpha-toxin binding was reduced by the coaddition of added navive alpha-toxin, indicating that the binding is specific. Sucrose gradient analysis of detergent-extracted complexes of [125I]alpha-toxin-rabbit vagus nerves showed both high and low S-value peaks analogous to those observed with similarly treated alpha-toxin-rabbit erythrocyte preparations (P. Cassidy and S. Harshman, Biochemistry, in press).
摘要
葡萄球菌[125I]α毒素与兔迷走神经在体外的结合是一个可饱和的过程。添加天然α毒素会使放射性标记的α毒素结合减少，这表明该结合具有特异性。对经去污剂提取的[125I]α毒素 - 兔迷走神经复合物进行蔗糖梯度分析，显示出高S值和低S值峰，这与用类似处理的α毒素 - 兔红细胞制剂观察到的峰类似（P. 卡西迪和S. 哈什曼，《生物化学》，即将发表）。
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3
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J Biol Chem. 1973 Aug 10;248(15):5545-6.
4
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5
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