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[恒定磁场对家兔海马癫痫病灶的影响]

[Effect of a constant magnetic field on hippocampal epileptic foci in the rabbit].

作者信息

Tyvin L I

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1982 May-Jun;32(3):494-501.

PMID:7113452
Abstract

Rabbits with penicillin epileptogenic foci in the hippocampus were subjected to the action of a non-uniform magnetic field (MF) of magnetophores. The maximal induction of the field on the surface of the magnetophore was 30 mT, the gradient -- 30 mT/cm, and average induction in the region of the focus --0.5 mT. It has been shown that activity between seizures does not change under the action of MF, while the number of electrographic correlates of seizures sharply increases. Interhemispheric difference in the epileptiform activity in the left and right hippocampus detected in the control, is substantially intensified in the experimental animals. No weakening of the effect was observed for fifteen days from the moment of the field application. It is assumed that the effect of the magnetic field action on the organism is similar to the influence of hypoxia.

摘要

在海马体中带有青霉素致痫灶的兔子接受了磁体非均匀磁场(MF)的作用。磁体表面磁场的最大感应强度为30 mT,梯度为30 mT/cm,致痫灶区域的平均感应强度为0.5 mT。结果表明,在磁场作用下发作间期的活动没有变化,而癫痫发作的脑电图相关性数量急剧增加。在对照组中检测到的左右海马体癫痫样活动的半球间差异,在实验动物中显著增强。从施加磁场那一刻起的15天内未观察到效应减弱。据推测,磁场对机体的作用效果类似于缺氧的影响。

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