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婴儿早期尿中游离及结合型雌酮和雌二醇-17β

Urinary free and conjugated oestrone and oestradiol-17 beta in early infancy.

作者信息

Kuhnle U, Bidlingmaier F, Knorr D

出版信息

Acta Endocrinol (Copenh). 1982 May;100(1):150-3. doi: 10.1530/acta.0.1000150.

DOI:10.1530/acta.0.1000150
PMID:7113583
Abstract

Conjugated and free urinary oestrone and oestradiol-17 beta were determined by radioimmunoassay in 98 urine samples of 44 normal male and female infants ranging from 7 days to 2 years of age. Both sexes excreted significantly more oestrone and oestradiol-17 beta during the first 3 months of life compared to the end of the first year. Values peaked at the beginning of the second month. During the first 7 months of life, female infants excreted significantly more conjugated oestradiol-17 beta than oestrone, whereas male infants consistently excreted equal amounts of conjugated oestradiol-17 beta and oestrone. However, both sexes excreted significantly more free unconjugated oestrone than oestradiol-17 beta during the same period.

摘要

采用放射免疫分析法对44名年龄在7天至2岁之间的正常男、女婴幼儿的98份尿液样本中的结合型和游离型尿雌酮及雌二醇-17β进行了测定。与1岁末相比,两性在出生后的前3个月排出的雌酮和雌二醇-17β明显更多。数值在第二个月初达到峰值。在出生后的前7个月,女婴排出的结合型雌二醇-17β明显多于雌酮,而男婴排出的结合型雌二醇-17β和雌酮量始终相等。然而,在同一时期,两性排出的游离非结合型雌酮均明显多于雌二醇-17β。

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