Doumith R, de Gennes J L, Cabane J P, Zygelman N
Acta Endocrinol (Copenh). 1982 Jun;100(2):189-95. doi: 10.1530/acta.0.1000189.
A large pituitary prolactinoma was found in a mentally deficient 45 year old woman presenting with amenorrhoea, galactorrhoea, headache, anaemia and hypertension, and removed surgically. She was subsequently found to have multiple adrenal aldosterone-producing adenomas, a gastric schwannoma and colonic polyadenomas. All these tumors were also removed surgically. Despite the absence of parathyroid and islet-cell hyperplasia, this case seems to be a variant of multiple endocrine neoplasia (MEN) type I.
在一名45岁智力缺陷的女性中发现了一个大型垂体催乳素瘤,该患者表现为闭经、溢乳、头痛、贫血和高血压,并接受了手术切除。随后发现她患有多个肾上腺醛固酮分泌腺瘤、一个胃神经鞘瘤和结肠息肉腺瘤。所有这些肿瘤也都进行了手术切除。尽管没有甲状旁腺和胰岛细胞增生,但该病例似乎是I型多发性内分泌肿瘤(MEN)的一种变体。