Mason E E, Printen K J, Blommers T J, Scott D H
Int J Obes. 1978;2(2):197-206.
Over 625 patients having gastric bypass for the treatment of morbid obesity are currently being followed at the University of Iowa. Many innovations have increased operative exposure, greatly reduced operating time, and improved the effectiveness and safety of the operation. Recent weight figures show that a 55 percent loss of excess weight can be expected. Several comparative studies between gastric and jejunoileal bypass show that gastric bypass, while producing identical weight loss, has few of the many complications such as liver failure, renal and gallstone formation, diarrhea, enteritis, that are commonly associated with jejunoileal bypass. Stomal ulcer occurrence has been only 2 percent. Imporvements in diabetes mellitus and hypertension can be expected with weight loss. Other effects of gastric bypass were determined by use of a questionnaire. It is concluded, by surgeons having experience with both gastric and jejunoileal bypass, that gastric bypass is the treatment of choice for morbid obesity when nonoperative measures fail.
目前，爱荷华大学正在对625多名接受胃旁路手术治疗病态肥胖症的患者进行跟踪随访。许多创新措施增加了手术视野，大幅缩短了手术时间，并提高了手术的有效性和安全性。近期的体重数据显示，预计超重部分可减轻55%。几项胃旁路手术和空肠回肠旁路手术的对比研究表明，胃旁路手术虽然减重效果相同，但很少出现空肠回肠旁路手术常见的诸多并发症，如肝衰竭、肾结石和胆结石形成、腹泻、肠炎等。吻合口溃疡的发生率仅为2%。随着体重减轻，预计糖尿病和高血压情况会有所改善。胃旁路手术的其他影响通过问卷调查确定。有胃旁路手术和空肠回肠旁路手术经验的外科医生得出结论，当非手术措施无效时，胃旁路手术是治疗病态肥胖症的首选方法。
